Yubing Xia

MSc student
Email
yxia266obfuscate@uwo.ca

I’ve always been intrigued by how the immune system distinguishes self from non‑self, and how those decisions influence disease progression. That curiosity led me from studying graft‑versus‑host disease to my current project, which looks at how immune cells behave in aggressive breast cancers. Using single‑cell and spatial transcriptomics alongside machine‑learning analyses, I’m investigating how both blood‑borne and tumor‑based immune cells react to treatment and hoping to uncover insights that could benefit patients. When I’m not in the lab, I love hiking, exercising, and relaxing with my cat Qiuqiu.

Education 🎓

  • Sept 2025-present: MSc, Anatomy & Cell Biology, Western University
  • 2018 - 2023: BSc, Double Major in Immunology and Statistics, University of Toronto

Research 🔍

  • 2025 - present: Integrated spatial and systemic immune profiling for predictive biomarker discovery in high-risk breast cancer (Dumeaux Lab, Western)
  • 2022 - 2023: Single Cell Analysis on myeloid cell activities in acute Graft-versus-Host Disease. Presenter, (ISSRP, Crome Lab, Toronto)
  • 2021 - 2023: Analysis on scRNA-seq dataset of developmental thymocytes (Anderson Lab, Toronto) Characterizing transcriptional heterogeneity in microbial communities

Award / Fellowship

  • 2025 - 2026: Translational Breast Cancer Research Unit (TBCRU) MSc fellowship, supported by Breast Cancer Canada
  • 2022: Immunology Summer Student Research Project (ISSRP)
  • 2022: Second place award, Ontario-Quebec Undergraduate Immunology Conference
  • 2021: Immunology Summer Student Research Project (ISSRP)

Previous Publications

Reid KT, Colpitts SJ, Mathews JA, Santos Carreira A, Murphy JM, Borovsky DT, Jegatheeswaran S, Cui W, Alfaro Moya T, Sachewsky N, An J, Xia Y, Mortha A, Lee JB, Zhang L, Novitzky-Basso I, Mattsson J, Crome SQ. Cell therapy with human IL-10-producing ILC2s limits xenogeneic graft-versus-host disease by inhibiting pathogenic T cell responses. Cell Rep. 2025 Jan 28;44(1):115102. doi: 10.1016/j.celrep.2024.115102. Epub 2024 Dec 24. PMID: 39721022.